Yes, it's over. You've returned to work, your time off is in the review mirror, and it's back to the daily grind.
While, technically, there's nothing you need to do except get back to work, it's wise to make sure all of your out-of-office messages are now turned off. While they should be, technology hasn't earned a reputation for being unreliable for nothing, so it's a good idea to double-check.